Set in Melbourne in the 1960s, Ms Fisher's Modern Murder Mysteries revolves around the personal and professional life of Peregrine Fisher, daughter of Phryne’s half sister Annabelle (a result of an affair that Phryne’s father had), who inherits a fortune when the famous aunt she never knew goes missing over the highlands of New Guinea. Peregrine sets out to become a world-class private detective in her own right, guided by a group of exceptional women in The Adventuresses' Club, of which her aunt was also a member.